mRNA quality control goes transcriptional.
Eukaryotic mRNAs are extensively processed to generate functional transcripts, which are 5' capped, spliced and 3' polyadenylated. Accumulation of unprocessed (aberrant) mRNAs can be deleterious for the cell, hence processing fidelity is closely monitored by QC (quality control) mechanisms...
| Auteurs principaux: | , |
|---|---|
| Format: | Journal article |
| Langue: | English |
| Publié: |
2013
|