Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity.
BALB/c mice infected with the intracellular protozoan Leishmania major mount a T helper cell 2 (Th2) response that fails to control growth of the parasite and results in the development of visceral leishmaniasis. Separation of CD4+ T cells into CD45RBhigh and CD45RBlow subsets showed that the L. maj...
Những tác giả chính: | Powrie, F, Correa-Oliveira, R, Mauze, S, Coffman, R |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
1994
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Những quyển sách tương tự
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CD45RBHIGH CD4+ T-CELLS INDUCE A PATHOGENIC TH1 RESPONSE IN THE COLON WHEN TRANSFERRED TO C-B-17 SCID MICE WHICH IS PREVENTED BY CO-TRANSFER OF THE CD45RBLOW POPULATION
Bằng: Powrie, F, et al.
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REGULATION OF PATHOGENIC TH1 RESPONSES AGAINST IMMUNOLOGICAL SELF-ANTIGENS BY CD45RBLOW CD4+ T-CELLS
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Inflammatory bowel disease in C.B-17 scid mice reconstituted with the CD45RBhigh subset of CD4+ T cells.
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CD38+ CD45RB(low) CD4+ T cells: a population of T cells with immune regulatory activities in vitro.
Bằng: Read, S, et al.
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CD4+CD25+cells reverse established colitis in the CD4+CD45RBhigh adoptive transfer model of colitis.
Bằng: Mottet, C, et al.
Được phát hành: (2002)