The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

Semaphorins are a family of secreted and membrane-bound proteins, known to regulate axonal pathfinding. Sema4D, also called CD100, was first isolated in the immune system where it is involved in B and T cell activation. We found that in the mouse, Sema4D is expressed in cells throughout the CNS whit...

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Մատենագիտական մանրամասներ
Հիմնական հեղինակներ: Moreau-Fauvarque, C, Kumanogoh, A, Camand, E, Jaillard, C, Barbin, G, Boquet, I, Love, C, Jones, E, Kikutani, H, Lubetzki, C, Dusart, I, Chédotal, A
Ձևաչափ: Journal article
Լեզու:English
Հրապարակվել է: 2003

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