Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension
It is well established that gene interactions influence common human diseases, but to date linkage studies have been constrained to searching for single genes across the genome. We applied a novel approach to uncover significant gene-gene interactions in a systematic two-dimensional (2D) genome-scan...
Main Authors: | Tzenova Bell, J, Wallace, C, Dobson, R, Wiltshire, S, Mein, C, Pembroke, J, Brown, M, Clayton, D, Samani, N, Dominiczak, A, Webster, J, Lathrop, G, Connell, J, Munroe, P, Caulfield, M, Farrall, M |
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格式: | Journal article |
語言: | English |
出版: |
Oxford University Press
2006
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