Stereoselective methodology for 1-aryl-1-alkyl epoxides via chromium tricarbonyl complexes
Treatment of (1RS, SSR)-(1-phenylsulfinyl-2-valeryl benzene) chromium tricarbonyl 2 with a sulfur ylide results in a highly diastereoselective epoxide formation (d.s.>96:4). Regioselective opening of the epoxide, employing an in situ trapping protocol, allows the synthesis of a highly functio...
| Үндсэн зохиолчид: | , , |
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| Формат: | Journal article |
| Хэвлэсэн: |
1997
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