IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease

<p style="text-align:justify;"> <b>Background & Aims:</b> Identification of inflammatory bowel disease (IBD) susceptibility genes is key to understanding pathogenic mechanisms. Recently, the North American IBD Genetics Consortium provided compelling evidence for...

Bibliografske podrobnosti
Main Authors:	Tremelling, M, Cummings, F, Fisher, SA, Mansfield, J, Gwilliam, R, Keniry, A, Nimmo, ER, Drummond, H, Onnie, CM, Prescott, NJ, Sanderson, J, Bredin, F, Berzuini, C, Forbes, A, Lewis, CM, Cardon, L, Deloukas, P, Jewell, D, Mathew, CG, Parkes, M, Satsangi, J
Format:	Journal article
Jezik:	English
Izdano:	Elsevier 2007

Podobne knjige/članki

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
od: Fisher, SA, et al.
Izdano: (2008)

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease.
od: Fisher, SA, et al.
Izdano: (2008)

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility.
od: Parkes, M, et al.
Izdano: (2007)

Molecular genetics of Crohn's disease: recent advances.
od: Satsangi, J, et al.
Izdano: (1998)

Genetics of inflammatory bowel disease.
od: Satsangi, J, et al.
Izdano: (1998)

Susceptibility loci in inflammatory bowel disease.
od: Parkes, M, et al.
Izdano: (1996)

Cytokine production in inflammatory bowel disease.
od: Satsangi, J, et al.
Izdano: (1994)

New genes in inflammatory bowel disease: lessons for complex diseases?
od: Gaya, DR, et al.
Izdano: (2006)

DLG5 variants do not influence susceptibility to inflammatory bowel disease in the Scottish population
od: Noble, CL, et al.
Izdano: (2015)

Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
od: Anderson, C, et al.
Izdano: (2009)

Are cytokine gene polymorphisms important in the pathogenesis of inflammatory bowel disease?
od: Satsangi, J, et al.
Izdano: (1996)

The genetics of inflammatory bowel disease.
od: Satsangi, J, et al.
Izdano: (1997)

Genetics of inflammatory bowel disease: scientific and clinical implications
od: Satsangi, J, et al.
Izdano: (2003)

NOD2/CARD15 and the Paneth cell: another piece in the genetic jigsaw of inflammatory bowel disease
od: Aldhous, MC, et al.
Izdano: (2003)

Ulcerative colitis is more strongly linked to chromosome 12 than Crohn's disease.
od: Parkes, M, et al.
Izdano: (2001)

Genetics of ulcerative colitis.
od: Satsangi, J, et al.
Izdano: (1996)

The IBD2 locus shows linkage heterogeneity between ulcerative colitis and Crohn disease.
od: Parkes, M, et al.
Izdano: (2000)

Inflammatory bowel disease and the X chromosome.
od: Hayward, P, et al.
Izdano: (1996)

Evidence for inflammatory bowel disease of a susceptibility locus on the X chromosome.
od: Vermeire, S, et al.
Izdano: (2001)

Genetics of inflammatory bowel disease.
od: Satsangi, J, et al.
Izdano: (1994)

Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn’s disease
od: Polley, S, et al.
Izdano: (2016)

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn’s disease
od: Noble, C, et al.
Izdano: (2005)

Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
od: de Lange, K, et al.
Izdano: (2017)

Exploring the hidden heritability of inflammatory bowel disease
od: Satsangi, J, et al.
Izdano: (2011)

Genetics of inflammatory bowel disease: a reappraisal.
od: Orchard, T, et al.
Izdano: (2000)

Clinical patterns of familial inflammatory bowel disease.
od: Satsangi, J, et al.
Izdano: (1996)

Is interleukin-6 important in inflammatory bowel disease?
od: Koss, K, et al.
Izdano: (2000)

The impact of NOD2 variants on fecal microbiota in Crohn's Disease and controls without gastrointestinal disease
od: Kennedy, N, et al.
Izdano: (2018)

Inflammatory bowel disease: progress toward a gene.
od: van Heel, D, et al.
Izdano: (2000)

Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.
od: Cummings, JR, et al.
Izdano: (2007)

Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease.
od: Satsangi, J, et al.
Izdano: (1996)

Review article: the management of severe Crohn's disease.
od: Parkes, M, et al.
Izdano: (2001)

Investigation of NOD1/CARD4 variation in inflammatory bowel disease using a haplotype-tagging strategy
od: Van Limbergen, J, et al.
Izdano: (2007)

The genetics of NOD-like receptors in Crohn's disease.
od: Cummings, JR, et al.
Izdano: (2010)

Crohn’s disease or Crohn’s diseases?
od: Arnott, IDR, et al.
Izdano: (2003)

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn’s disease
od: Lee, J, et al.
Izdano: (2017)

Infliximab use in Crohn's disease: impact on health care resources in the UK.
od: Jewell, D, et al.
Izdano: (2005)

Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12.
od: Satsangi, J, et al.
Izdano: (1996)

Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7
od: Luo, Y, et al.
Izdano: (2017)

Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway
od: Nimmo, ER, et al.
Izdano: (2011)