Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.

Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release.

Nicotinic acid adenine dinucleotide phosphate (NAADP, 1) is the most potent intracellular Ca2+ mobilizing agent in important mammalian cells and tissues, yet the identity of the NAADP receptor is elusive. Significantly, the coenzyme NADP is completely inactive in this respect. Current studies are re...

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Bibliographic Details
Main Authors:	Dowden, J, Berridge, G, Moreau, C, Yamasaki, M, Churchill, G, Potter, B, Galione, A
Format:	Journal article
Language:	English
Published:	2006

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