Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.

Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.

1. The beta-cell K(ATP) channel is composed of two types of subunit - the inward rectifier K(+) channel (Kir6.2) which forms the channel pore, and the sulphonylurea receptor (SUR1), which serves as a regulatory subunit. The N-terminus of Kir6.2 is involved in transduction of sulphonylurea binding in...

Полное описание

Библиографические подробности
Главные авторы:	Hansen, A, Hansen, J, Carr, R, Ashcroft, F, Wahl, P
Формат:	Journal article
Язык:	English
Опубликовано:	2005

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