Monocytic origin of foam cells in human atherosclerotic plaques.

Foam cells in 4 human atherosclerotic plaques reacted with 3 rat monoclonal antibodies directed against T.200 ('anti-leucocyte common' antibody), HLA-Class II molecules and macrophage cytoplasm, respectively. Smooth muscle cells did not react. The results support the view that foam cells a...

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Bibliografiska uppgifter
Huvudupphovsmän: Aqel, N, Ball, R, Waldmann, H, Mitchinson, M
Materialtyp: Journal article
Språk:English
Publicerad: 1984
Beskrivning
Sammanfattning:Foam cells in 4 human atherosclerotic plaques reacted with 3 rat monoclonal antibodies directed against T.200 ('anti-leucocyte common' antibody), HLA-Class II molecules and macrophage cytoplasm, respectively. Smooth muscle cells did not react. The results support the view that foam cells are monocyte-derived macrophages.