Rapid and efficient DNA strand cross-linking by click chemistry.
Click chemistry has been used to covalently cross-link complementary DNA strands between bases to form very stable duplexes. Several alkyne- and azide-modified uracil monomers were used to evaluate the effect of the linkers on the efficiency of the click reaction. All cross-linked duplexes had much...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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