Regional acidosis locally inhibits but remotely stimulates Ca2+ waves in ventricular myocytes.

AIMS: Spontaneous Ca2+ waves in cardiomyocytes are potentially arrhythmogenic. A powerful controller of Ca2+ waves is the cytoplasmic H+ concentration ([H+]i), which fluctuates spatially and temporally in conditions such as myocardial ischaemia/reperfusion. H+-control of Ca2+ waves is poorly underst...

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Những tác giả chính: Ford, K, Moorhouse, E, Bortolozzi, M, Richards, M, Swietach, P, Vaughan-Jones, R
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Oxford University Press 2017