Role of carbonic anhydrase catalysis and gap junctional coupling in regulating ph in pancreatic ductal adenocarcinoma (PDAC)
<p>Pancreatic ductal adenocarcinoma (PDAC) develops from the acinar cells of the exocrine pancreas. PDAC tumours are hypoxic and produce a characteristically acidic microenvironment hypothesised to favour more aggressive phenotypes. My thesis work concerned the acid-handling mechanisms in 2-D...
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2017
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