The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep

Investigations into schizophrenia have revealed a high incidence of comorbidity with disturbed sleep and circadian timing. Acknowledging this comorbidity on a dimensional level, we tested prospectively whether subclinical psychotic symptoms are more prevalent in individuals with insomnia. An insomni...

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Detalhes bibliográficos
Principais autores: Cosgrave, J, Haines, R, van Heugten-van der Kloet, D, Purple, R, Porcheret, K, Foster, R, Wulff, K
Formato: Journal article
Publicado em: Elsevier 2017
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author Cosgrave, J
Haines, R
van Heugten-van der Kloet, D
Purple, R
Porcheret, K
Foster, R
Wulff, K
author_facet Cosgrave, J
Haines, R
van Heugten-van der Kloet, D
Purple, R
Porcheret, K
Foster, R
Wulff, K
author_sort Cosgrave, J
collection OXFORD
description Investigations into schizophrenia have revealed a high incidence of comorbidity with disturbed sleep and circadian timing. Acknowledging this comorbidity on a dimensional level, we tested prospectively whether subclinical psychotic symptoms are more prevalent in individuals with insomnia. An insomnia group (n = 21) and controls (n = 22) were recruited on their subjective sleep quality, recorded actigraphically for 3 weeks and assessed for psychotic-like experiences with The Prodromal Questionnaire-16. Using multivariate Poisson regression analyses, we found that objective and subjective sleep measures interact to predict the highest risk for psychotic experiences. Objective measures of sleep and statistical modelling are rarely used in either clinical trials or practice for schizophrenia, yet this study highlights their value in these areas.
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spelling oxford-uuid:3cbe644c-c7a1-446e-9e09-e0da4b78032a2022-03-26T14:15:26ZThe interaction between subclinical psychotic experiences, insomnia and objective measures of sleepJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3cbe644c-c7a1-446e-9e09-e0da4b78032aSymplectic Elements at OxfordElsevier2017Cosgrave, JHaines, Rvan Heugten-van der Kloet, DPurple, RPorcheret, KFoster, RWulff, KInvestigations into schizophrenia have revealed a high incidence of comorbidity with disturbed sleep and circadian timing. Acknowledging this comorbidity on a dimensional level, we tested prospectively whether subclinical psychotic symptoms are more prevalent in individuals with insomnia. An insomnia group (n = 21) and controls (n = 22) were recruited on their subjective sleep quality, recorded actigraphically for 3 weeks and assessed for psychotic-like experiences with The Prodromal Questionnaire-16. Using multivariate Poisson regression analyses, we found that objective and subjective sleep measures interact to predict the highest risk for psychotic experiences. Objective measures of sleep and statistical modelling are rarely used in either clinical trials or practice for schizophrenia, yet this study highlights their value in these areas.
spellingShingle Cosgrave, J
Haines, R
van Heugten-van der Kloet, D
Purple, R
Porcheret, K
Foster, R
Wulff, K
The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep
title The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep
title_full The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep
title_fullStr The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep
title_full_unstemmed The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep
title_short The interaction between subclinical psychotic experiences, insomnia and objective measures of sleep
title_sort interaction between subclinical psychotic experiences insomnia and objective measures of sleep
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