A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
Maturity-onset diabetes of the young (MODY) is a heterogeneous single gene disorder characterized by non-insulin-dependent diabetes, an early onset and autosomal dominant inheritance. Mutations in six genes have been shown to cause MODY. Approximately 15-20% of families fitting MODY criteria do not...
Main Authors: | Frayling, T, Lindgren, C, Chevre, J, Menzel, S, Wishart, M, Benmezroua, Y, Brown, A, Evans, J, Rao, P, Dina, C, Lecoeur, C, Kanninen, T, Almgren, P, Bulman, M, Wang, Y, Mills, J, Wright-Pascoe, R, Mahtani, M, Prisco, F, Costa, A, Cognet, I, Hansen, T, Pedersen, O, Ellard, S, Tuomi, T |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2003
|
相似书籍
-
A genome scan reveals heterogeneity among European families with maturity onset diabetes of the young
由: Frayling, T, et al.
出版: (2001) -
Contribution of known and unknown susceptibility genes to early-onset diabetes in scandinavia: evidence for heterogeneity.
由: Lindgren, C, et al.
出版: (2002) -
Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study.
由: Lindgren, C, et al.
出版: (2002) -
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
由: Demenais, F, et al.
出版: (2003) -
Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes.
由: Holmkvist, J, et al.
出版: (2008)