Stomach dose-volume parameters and clinical factors predict acute toxicity in pancreatic cancer chemoradiotherapy

Gastrointestinal (GI) toxicity impedes dose escalation and likelihood of cure in chemoradiotherapy (CRT) for hepatobiliary malignancies. The risk of toxicity can depend on clinical and radiotherapy (RT) dose-volume metrics. We aimed to identify predictive factors using data from two prospective phas...

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Detalles Bibliográficos
Main Authors: Holyoake, D, Partridge, M, Hurt, C, Mukherjee, S, Hawkins, M
Formato: Conference item
Publicado: Elsevier 2017
Descripción
Summary:Gastrointestinal (GI) toxicity impedes dose escalation and likelihood of cure in chemoradiotherapy (CRT) for hepatobiliary malignancies. The risk of toxicity can depend on clinical and radiotherapy (RT) dose-volume metrics. We aimed to identify predictive factors using data from two prospective phase-II clinical trials of locally-advanced pancreatic cancer (LAPC).