Sequence effects of single base loops in intramolecular quadruplex DNA.

We have examined the properties of intramolecular G-quadruplexes in which the G3 tracts are separated by single base loops. The most stable complex contained 1',2'-dideoxyribose in all three loops, while loops containing T and C were slightly less stable (by about 2 degrees C). Quadruplexe...

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Detalhes bibliográficos
Main Authors: Rachwal, P, Brown, T, Fox, K
Formato: Journal article
Idioma:English
Publicado em: 2007