Difluoroalkylation of tertiary amides and lactams by an iridium-catalyzed reductive reformatsky reaction
An iridium-catalyzed, reductive alkylation of abundant tertiary lactams and amides using 1-2 mol % of Vaska's complex (IrCl(CO)(PPh<sub>3</sub>)<sub>2</sub>), tetramethyldisiloxane (TMDS), and difluoro-Reformatsky reagents (BrZnCF<s...
Váldodahkkit: | , , |
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Materiálatiipa: | Journal article |
Giella: | English |
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ACS Publications
2022
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