Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex were examined for changes in Alzheimer's disease by use of both neurosurgical and autopsy samples. Uptake of [3H]serotonin, binding of [3H]imipramine, and content of indolamines were all significantly reduc...

書誌詳細
主要な著者:	Bowen, D, Allen, S, Benton, J, Goodhardt, M, Haan, E, Palmer, A, Sims, N, Smith, C, Spillane, J, Esiri, M, Neary, D, Snowdon, J, Wilcock, G, Davison, A
フォーマット:	Journal article
言語:	English
出版事項:	1983

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