Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease.

Markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex were examined for changes in Alzheimer's disease by use of both neurosurgical and autopsy samples. Uptake of [3H]serotonin, binding of [3H]imipramine, and content of indolamines were all significantly reduc...

Podrobná bibliografie
Hlavní autoři:	Bowen, D, Allen, S, Benton, J, Goodhardt, M, Haan, E, Palmer, A, Sims, N, Smith, C, Spillane, J, Esiri, M, Neary, D, Snowdon, J, Wilcock, G, Davison, A
Médium:	Journal article
Jazyk:	English
Vydáno:	1983

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