Studies of immunity and bacterial invasiveness in mice given a recombinant salmonella vector encoding murine interleukin-6.
Interleukin-6 (IL-6) was expressed in Salmonella typhimurium in an attempt to increase the mucosal immune response against the bacterium. Murine IL-6 was PCR amplified from cDNA, cloned, sequenced, and found to be functionally active when expressed in S. typhimurium BRD509, the (delta)aroA (delta)ar...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1996
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