C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence

<p><em>C-</em>Mannosylation is a common modification of thrombospondin type 1 repeats present in metazoans and recently identified also in apicomplexan parasites. This glycosylation is mediated by enzymes of the DPY19 family that transfer &alpha;-mannoses to tryptophan residues...

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Bibliographic Details
Main Authors: Albuquerque-Wendt, A, Jacot, D, Dos Santos Pacheco, N, Seegers, C, Zarnovican, P, Buettner, FFR, Bakker, H, Soldati-Favre, D, Routier, FH
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2019