Human T-follicular helper and T-follicular regulatory cell maintenance is independent of germinal centers.

The monoclonal anti-CD20 antibody rituximab (RTX) depletes B cells in the treatment of lymphoma and autoimmune disease, and contributes to alloantibody reduction in transplantation across immunologic barriers. The effects of RTX on T cells are less well described. T-follicular helper (Tfh) cells pro...

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Detalles Bibliográficos
Autores principales: Wallin, E, Jolly, E, Suchánek, O, Bradley, J, Espéli, M, Jayne, DR, Linterman, M, Smith, K
Formato: Journal article
Lenguaje:English
Publicado: 2014