Efficacy of the MMP inhibitor MMI270 against lung metastasis following removal of orthotopically transplanted human colon cancer in rat.

Efficacy of the MMP inhibitor MMI270 against lung metastasis following removal of orthotopically transplanted human colon cancer in rat.

We have investigated the antitumor effects of synthetic MMP inhibitor MMI270 against postoperative lung metastasis from colon cancer in nude rat. The KM12SM human colon cancer cells were injected into the cecal wall, and at 5 weeks after the injection, the cecum was removed including the tumor. Then...

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Bibliographic Details
Main Authors:	Ogata, Y, Matono, K, Nakajima, M, Sasatomi, T, Mizobe, T, Nagase, H, Shirouzu, K
Format:	Journal article
Language:	English
Published:	2006

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