Activation-induced markers detect vaccine-specific CD4⁺ T cell responses not measured by assays conventionally used in clinical trials

Immunogenicity of T cell-inducing vaccines, such as viral vectors or DNA vaccines and Bacillus Calmette-Guérin (BCG), are frequently assessed by cytokine-based approaches. While these are sensitive methods that have shown correlates of protection in various vaccine studies, they only identify a smal...

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Những tác giả chính: Bowyer, G, Rampling, T, Powlson, J, Morter, R, Wright, D, Hill, A, Ewer, K
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: MDPI 2018