Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation.

Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation.

BACKGROUND: The African trypanosome Trypanosoma brucei is covered with a dense layer of Variant Surface Glycoprotein (VSG), which protects it from lysis by host complement via the alternative pathway in the mammalian bloodstream. Blocking VSG synthesis by the induction of VSG RNAi triggers an unusu...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Smith, T, Vasileva, N, Gluenz, E, Terry, S, Portman, N, Kramer, S, Carrington, M, Michaeli, S, Gull, K, Rudenko, G
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	Public Library of Science 2009

Παρόμοια τεκμήρια

Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation.
ανά: Terry K Smith, κ.ά.
Έκδοση: (2009-10-01)

Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei
ανά: Ooi, C, κ.ά.
Έκδοση: (2018)

Proteomics and the Trypanosoma brucei cytoskeleton: advances and opportunities.
ανά: Portman, N, κ.ά.
Έκδοση: (2012)

Ultrastructural investigation methods for Trypanosoma brucei.
ανά: Höög, J, κ.ά.
Έκδοση: (2010)

The heart of darkness: growth and form of Trypanosoma brucei in the tsetse fly.
ανά: Sharma, R, κ.ά.
Έκδοση: (2009)

A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod.
ανά: Lacomble, S, κ.ά.
Έκδοση: (2009)

The heart of darkness : growth and form of Trypanosoma brucei in the tsetse fly.
ανά: Kumar Sharma, Reuben Sunil, κ.ά.
Έκδοση: (2009)

Identification of paralogous life-cycle stage specific cytoskeletal proteins in the parasite Trypanosoma brucei
ανά: Portman, N, κ.ά.
Έκδοση: (2014)

Functional characterization of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages.
ανά: Gluenz, E, κ.ά.
Έκδοση: (2008)

Structural asymmetry and discrete nucleic acid subdomains in the Trypanosoma brucei kinetoplast.
ανά: Gluenz, E, κ.ά.
Έκδοση: (2007)

Functional characterisation of cohesin subunit SCC1 in Trypanosoma brucei and dissection of mutant phenotypes in two life cycle stages.
ανά: Sharma, Reuben Sunil Kumar, κ.ά.
Έκδοση: (2008)

A protein-protein interaction map of the Trypanosoma brucei paraflagellar rod.
ανά: Sylvain Lacomble, κ.ά.
Έκδοση: (2009-11-01)

Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei.
ανά: Povelones, M, κ.ά.
Έκδοση: (2012)

Histone H1 plays a role in heterochromatin formation and VSG expression site silencing in Trypanosoma brucei.
ανά: Megan L Povelones, κ.ά.
Έκδοση: (2012-01-01)

The kinetoplast duplication cycle in Trypanosoma brucei is orchestrated by cytoskeleton-mediated cell morphogenesis.
ανά: Gluenz, E, κ.ά.
Έκδοση: (2011)

Variant surface glycoprotein synthesis and cell cycle progression in Trypanosoma brucei
ανά: Wand, N, κ.ά.
Έκδοση: (2011)

Blocking Synthesis of the Variant Surface Glycoprotein Coat in Trypanosoma brucei Leads to an Increase in Macrophage Phagocytosis Due to Reduced Clearance of Surface Coat Antibodies
ανά: Cheung, J, κ.ά.
Έκδοση: (2016)

T-tubulin in Trypanosoma brucei
ανά: Scott, V, κ.ά.
Έκδοση: (1996)

Variant Surface Glycoprotein gene repertoires in <it>Trypanosoma brucei </it>have diverged to become strain-specific
ανά: Sharma Reuben, κ.ά.
Έκδοση: (2007-07-01)

Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma brucei.
ανά: Sasse, R, κ.ά.
Έκδοση: (1988)

Purification and assembly in vitro of tubulin from Trypanosoma brucei brucei.
ανά: MacRae, T, κ.ά.
Έκδοση: (1990)

A new function of Trypanosoma brucei mitochondrial topoisomerase II is to maintain kinetoplast DNA network topology.
ανά: Lindsay, M, κ.ά.
Έκδοση: (2008)

The glycosylation of the variant surface glycoproteins and procyclic acidic repetitive proteins of Trypanosoma brucei
ανά: Mehlert, A, κ.ά.
Έκδοση: (1998)

Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes.
ανά: Sheader, K, κ.ά.
Έκδοση: (2005)

Partitioning of large and minichromosomes in Trypanosoma brucei.
ανά: Ersfeld, K, κ.ά.
Έκδοση: (1997)

Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis
ανά: Gustavo Bravo Ruiz, κ.ά.
Έκδοση: (2022-04-01)

Nuclear and genome organization of Trypanosoma brucei.
ανά: Ersfeld, K, κ.ά.
Έκδοση: (1999)

The mitotic stability of the minichromosomes of Trypanosoma brucei.
ανά: Wickstead, B, κ.ά.
Έκδοση: (2003)

Turnover of Variant Surface Glycoprotein in Trypanosoma brucei Is Not Altered in Response to Specific Silencing
ανά: Mohamed Sharif, κ.ά.
Έκδοση: (2022-08-01)

The structural mechanics of cell division in Trypanosoma brucei.
ανά: Vaughan, S, κ.ά.
Έκδοση: (2008)

The cell division cycle of Trypanosoma brucei brucei: timing of event markers and cytoskeletal modulations.
ανά: Sherwin, T, κ.ά.
Έκδοση: (1989)

THE CELL-DIVISION CYCLE OF TRYPANOSOMA-BRUCEI-BRUCEI - TIMING OF EVENT MARKERS AND CYTOSKELETAL MODULATIONS
ανά: Sherwin, T, κ.ά.
Έκδοση: (1989)

Targeting of cytoskeletal proteins to the flagellum of Trypanosoma brucei.
ανά: Ersfeld, K, κ.ά.
Έκδοση: (2001)

Mechanisms Mediating Antigenic Variation in Trypanosoma brucei
ανά: Rudenko Gloria
Έκδοση: (1999-01-01)

A new generation of T7 RNA polymerase-independent inducible expression plasmids for Trypanosoma brucei
ανά: Sunter, J, κ.ά.
Έκδοση: (2012)

Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor
ανά: Olivia J. S. Macleod, κ.ά.
Έκδοση: (2022-08-01)

Genome-wide <it>in silico </it>screen for CCCH-type zinc finger proteins of <it>Trypanosoma brucei</it>, <it>Trypanosoma cruzi </it>and <it>Leishmania major</it>
ανά: Carrington Mark, κ.ά.
Έκδοση: (2010-05-01)

Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei.
ανά: Alsford, S, κ.ά.
Έκδοση: (2001)

Perturbation of phosphatidylethanolamine synthesis affects mitochondrial morphology and cell-cycle progression in procyclic-form Trypanosoma brucei.
ανά: Signorell, A, κ.ά.
Έκδοση: (2009)

Evidence for a Mr 88,000 glycoprotein with a transmembrane association to a unique flagellum attachment region in Trypanosoma brucei.
ανά: Woods, A, κ.ά.
Έκδοση: (1989)