A serpin with a finger in many PAI’s: PAI-1’s central function in thromboinflammation and cardiovascular disease
Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor (serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). Turbulence in the levels of PAI-1 tilts the...
| Main Authors: | , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Frontiers Media
2021
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