A serpin with a finger in many PAI’s: PAI-1’s central function in thromboinflammation and cardiovascular disease

Plasminogen activator inhibitor 1 (PAI-1) is a member of the serine protease inhibitor (serpin) superfamily. PAI-1 is the principal inhibitor of the plasminogen activators, tissue plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). Turbulence in the levels of PAI-1 tilts the...

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Detalhes bibliográficos
Principais autores: Morrow, GB, Whyte, C, Mutch, N
Formato: Journal article
Idioma:English
Publicado em: Frontiers Media 2021

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