Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa.

Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa.

HIV-specific CTL play a central role in immune control of HIV. The basis for understanding the success or failure of this immune response requires identification of the specific epitopes targeted by CTL. However, in populations most severely affected by the global epidemic, this fundamental knowledg...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Honeyborne, I, Rathod, A, Buchli, R, Ramduth, D, Moodley, E, Rathnavalu, P, Chetty, S, Day, C, Brander, C, Hildebrand, W, Walker, B, Kiepiela, P, Goulder, P
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	2006

Παρόμοια τεκμήρια

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.
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Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. (vol 177, pg 4699, 2006)
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Erratum: Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype (Journal of Immunology (2006) 177 (4699-4708))
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Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes.
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Targeting of a CD8 T cell env epitope presented by HLA-B*5802 is associated with markers of HIV disease progression and lack of selection pressure.
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Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.
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HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control.
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Rapid progressing allele HLA-B35 Px restricted anti-HIV-1 CD8+ T cells recognize vestigial CTL epitopes.
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Correction: Rapid Progressing Allele HLA-B35 Px Restricted Anti-HIV-1 CD8+ T Cells Recognize Vestigial CTL Epitopes.
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Έκδοση: (2016-01-01)

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Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restrieted gag epitope in chronic human immunodeficiency virus type 1 infection (vol 81, pg 8346, 2007)
ανά: Crawford, H, κ.ά.
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P09-19 LB. CTL escape mutations in gag epitopes restricted by protective HLA class I alleles cause substantial reductions in viral replication capacity
ανά: Walker B, κ.ά.
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Definition of peptide binding motifs amongst the HLA-A*30 allelic group.
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Rare HLA drive additional HIV evolution compared to more frequent alleles.
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