Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa.
HIV-specific CTL play a central role in immune control of HIV. The basis for understanding the success or failure of this immune response requires identification of the specific epitopes targeted by CTL. However, in populations most severely affected by the global epidemic, this fundamental knowledg...
Үндсэн зохиолчид: | Honeyborne, I, Rathod, A, Buchli, R, Ramduth, D, Moodley, E, Rathnavalu, P, Chetty, S, Day, C, Brander, C, Hildebrand, W, Walker, B, Kiepiela, P, Goulder, P |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
2006
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype.
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Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. (vol 177, pg 4699, 2006)
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Erratum: Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype (Journal of Immunology (2006) 177 (4699-4708))
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Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.
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