Soluble MICA as an independent prognostic factor for the overall survival and progression-free survival of multiple myeloma patients.
Major histocompatibility complex class I-related chain A (MICA) molecules are frequently expressed in lymphoproliferative malignancies including multiple myeloma (MM). MICA activates NK cells and co-stimulates T cells by interaction with its immunoreceptor NKG2D. In contrast, soluble MICA (sMICA) mo...
Main Authors: | Rebmann, V, Schütt, P, Brandhorst, D, Opalka, B, Moritz, T, Nowrousian, MR, Grosse-Wilde, H |
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Format: | Journal article |
Language: | English |
Published: |
2007
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