Analysis of tumor as an inverse problem provides a novel theoretical framework for understanding tumor biology and therapy

We use a novel “inverse problem” technique to construct a basic mathematical model of the interacting populations at the tumor-host interface. This approach assumes that invasive cancer is a solution to the set of state equations that govern the interactions of transformed and normal cells. By consi...

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Bibliographic Details
Main Authors: Gatenby, R, Maini, P, Gawlinski, E
Format: Journal article
Published: 2002