Protein aggregate-ligand binding assays based on microfluidic diffusional separation

The measurement of molecular interactions with pathological protein aggregates, including amyloid fibrils, is of central importance in the context of the development of diagnostic and therapeutic strategies against protein misfolding disorders. Probing such interactions by conventional methods can,...

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Bibliographic Details
Main Authors: Zhang, Y, Buell, A, Müller, T, De Genst, E, Benesch, J, Dobson, C, Knowles, T
Format: Journal article
Language:English
Published: Wiley 2016