Protein aggregate-ligand binding assays based on microfluidic diffusional separation

The measurement of molecular interactions with pathological protein aggregates, including amyloid fibrils, is of central importance in the context of the development of diagnostic and therapeutic strategies against protein misfolding disorders. Probing such interactions by conventional methods can,...

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Detalles Bibliográficos
Autores principales: Zhang, Y, Buell, A, Müller, T, De Genst, E, Benesch, J, Dobson, C, Knowles, T
Formato: Journal article
Lenguaje:English
Publicado: Wiley 2016