DNA modifications: naturally more error prone?

DNA modifications: naturally more error prone?

Epigenetic DNA modifications are essential for normal cell function in vertebrates, but they can also be hotspots of mutagenesis. Methylcytosine in particular has long been known to be less stable than other nucleotides and spontaneously deaminates to thymine. Beyond this well-established phenomenon...

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Bibliographic Details
Main Authors:	Tomkova, M, Schuster-Boeckler, P
Format:	Journal article
Published:	Cell Press 2018

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