A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage
The human nasopharynx contains a stable microbial ecosystem of commensal and potentially pathogenic bacteria, which can elicit protective primary and secondary immune responses. Experimental intranasal infection of human adults with the commensal Neisseria lactamica produced safe, sustained pharynge...
المؤلفون الرئيسيون: | Laver, JR, Gbesemete, D, Dale, AP, Pounce, ZC, Webb, CN, Roche, EF, Guy, JM, Berreen, G, Belogiannis, K, Hill, AR, Ibrahim, MM, Ahmed, M, Cleary, DW, Pandey, AK, Humphries, HE, Allen, L, de Graaf, H, Maiden, M, Faust, SN, Gorringe, AR, Read, RC |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
American Association for the Advancement of Science
2021
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مواد مشابهة
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Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection
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