A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage

A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage

The human nasopharynx contains a stable microbial ecosystem of commensal and potentially pathogenic bacteria, which can elicit protective primary and secondary immune responses. Experimental intranasal infection of human adults with the commensal Neisseria lactamica produced safe, sustained pharynge...

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Bibliografiske detaljer
Main Authors:	Laver, JR, Gbesemete, D, Dale, AP, Pounce, ZC, Webb, CN, Roche, EF, Guy, JM, Berreen, G, Belogiannis, K, Hill, AR, Ibrahim, MM, Ahmed, M, Cleary, DW, Pandey, AK, Humphries, HE, Allen, L, de Graaf, H, Maiden, M, Faust, SN, Gorringe, AR, Read, RC
Format:	Journal article
Sprog:	English
Udgivet:	American Association for the Advancement of Science 2021

Lignende værker

Neisseria lactamica Y92-1009 complete genome sequence.
af: Pandey, AK, et al.
Udgivet: (2017)

Nasal inoculation of the commensal Neisseria lactamica inhibits carriage of Neisseria meningitidis by young adults: A controlled human infection study.
af: Deasy, A, et al.
Udgivet: (2015)

Group A Streptococcus pharyngitis and pharyngeal carriage: A meta-analysis.
af: Jane Oliver, et al.
Udgivet: (2018-03-01)

Pharyngeal carriage of Neisseria species in the African meningitis belt
af: Diallo, K, et al.
Udgivet: (2016)

Microevolution of Neisseria lactamica during nasopharyngeal colonisation induced by controlled human infection
af: Pandey, A, et al.
Udgivet: (2018)

Evaluation of pharyngeal carriage of Neisseria meningitidis in Tehran, Iran
af: A. Fahimzad, et al.
Udgivet: (2022-01-01)

Clinical and epidemiological aspects of streptococcus pyogenes pharyngitis and carriage in Africa
af: Mark E. Engel, et al.
Udgivet: (2017-04-01)

Carriage and antimicrobial susceptibility of commensal Neisseria species from the human oropharynx
af: Victoria F. Miari, et al.
Udgivet: (2024-10-01)

Investigation of correlates of protection against pharyngeal carriage of Neisseria meningitidis genogroups W and Y in the African meningitis belt.
af: Cooper, L, et al.
Udgivet: (2017)

Pharyngeal carriage of Neisseria meningitidis in 2-19-year-old individuals in Uganda.
af: Caugant, D, et al.
Udgivet: (2006)

Investigation of correlates of protection against pharyngeal carriage of Neisseria meningitidis genogroups W and Y in the African meningitis belt.
af: Laura V Cooper, et al.
Udgivet: (2017-01-01)

Impact of meningococcal ACWY conjugate vaccines on pharyngeal carriage in adolescents: evidence for herd protection from the UK MenACWY programme
af: Carr, JP, et al.
Udgivet: (2022)

Effect of mupirocin treatment on nasal, pharyngeal, and perineal carriage of Staphylococcus aureus in healthy adults.
af: Wertheim, H, et al.
Udgivet: (2005)

‘Be on the TEAM’ Study (Teenagers Against Meningitis): protocol for a controlled clinical trial evaluating the impact of 4CMenB or MenB-fHbp vaccination on the pharyngeal carriage of meningococci in adolescents
af: Carr, J, et al.
Udgivet: (2020)

Density distribution of pharyngeal carriage of meningococcus in healthy young adults: new approaches to studying the epidemiology of colonization and vaccine indirect effects
af: Finn, A, et al.
Udgivet: (2016)

Frequency of pharyngeal Neisseria Carriage among 10-12 years old pupiles in Tehran, Iran
af: Pourmand MR (PhD), et al.
Udgivet: (2011-09-01)

Diverse proinflammatory response in pharyngeal epithelial cells upon interaction with Neisseria meningitidis carriage and invasive isolates
af: Alexander Persson, et al.
Udgivet: (2024-03-01)

The pharyngeal carriage of Haemophilus influenzae among healthy population in China: a systematic review and meta-analysis
af: Peng Yang, et al.
Udgivet: (2019-06-01)

B Part of It protocol: a cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage of Neisseria meningitidis in adolescents
af: Marshall, HS, et al.
Udgivet: (2018)

Characterizing the diversity and commensal origins of penA mosaicism in the genus Neisseria
af: Unitt, A, et al.
Udgivet: (2024)

Neisseria lactamica Y92–1009 complete genome sequence
af: Anish K. Pandey, et al.
Udgivet: (2017-07-01)

Correction to: Neisseria lactamica Y92–1009 complete genome sequence
af: Anish K. Pandey, et al.
Udgivet: (2018-02-01)

Group A beta-hemolytic streptococcal pharyngitis and carriage rate among Egyptian children: a case-control study
af: Shereen Mohamed Abd El-Ghany, et al.
Udgivet: (2015-09-01)

Ugly bugs in healthy guts! Carriage of multidrug-resistant and ESBL-producing commensal Enterobacteriaceae in the intestine of healthy Nepalese adults
af: Maharjan A, et al.
Udgivet: (2018-04-01)

‘Be on the TEAM’ Study (Teenagers Against Meningitis): protocol for a controlled clinical trial evaluating the impact of 4CMenB or MenB-fHbp vaccination on the pharyngeal carriage of meningococci in adolescents
af: Matthew D Snape, et al.
Udgivet: (2020-10-01)

Nasal and pharyngeal carriage of methicillin-resistant Staphylococcus sciuri among hospitalised patients and healthcare workers in a Serbian university hospital.
af: Ivana Cirkovic, et al.
Udgivet: (2017-01-01)

Acoustic Characteristics of Arabic Pharyngeal and Pharyngealized Consonants
af: Boxberger, Linda
Udgivet: (1981-01-01)

Pharyngeal Carriage of Beta-Haemolytic <i>Streptococcus</i> Species and Seroprevalence of Anti-Streptococcal Antibodies in Children in Bouaké, Côte d’Ivoire
af: Pacôme Monemo, et al.
Udgivet: (2020-11-01)

Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda
af: Irene Nayiga, et al.
Udgivet: (2017-04-01)

Outbreak strain characterisation and pharyngeal carriage detection following a protracted group B meningococcal outbreak in adolescents in South-West England
af: Stephen A. Clark, et al.
Udgivet: (2019-07-01)

PHARYNGITIS IN CHILDREN
af: T.A. Polunina, et al.
Udgivet: (2011-10-01)

PHARYNGITIS IN CHILDREN
af: T.A. Polunina, et al.
Udgivet: (2011-10-01)

Alternative molecular methods for improved detection of meningococcal carriage and measurement of bacterial density
af: Manigart, O, et al.
Udgivet: (2016)

Genetic diversity and carriage dynamics of Neisseria lactamica in infants.
af: Bennett, J, et al.
Udgivet: (2005)

Asymptomatic pharyngeal carriage rate of Streptococcus pyogenes, its associated factors and antibiotic susceptibility pattern among school children in Hawassa town, southern Ethiopia
af: Asrat Anja, et al.
Udgivet: (2019-09-01)

Nasopharyngeal Bacterial Carriage in the Conjugate Vaccine Era with a Focus on Pneumococci
af: V. T. Devine, et al.
Udgivet: (2015-01-01)

Dynamic Analysis of the Symbiotic Model of Commensalism and Parasitism with Harvesting in Commensal Populations
af: Nurmaini Puspitasari, et al.
Udgivet: (2021-04-01)

Pharyngeal Flap Operation
af: P. B. Sulakhe
Udgivet: (1968-12-01)

Primary pharyngeal tuberculosis
af: Gupta K, et al.
Udgivet: (2005-01-01)

Streptococcal acute pharyngitis
af: Lais Martins Moreira Anjos, et al.
Udgivet: (2014-07-01)