A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage

A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage

The human nasopharynx contains a stable microbial ecosystem of commensal and potentially pathogenic bacteria, which can elicit protective primary and secondary immune responses. Experimental intranasal infection of human adults with the commensal Neisseria lactamica produced safe, sustained pharynge...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Laver, JR, Gbesemete, D, Dale, AP, Pounce, ZC, Webb, CN, Roche, EF, Guy, JM, Berreen, G, Belogiannis, K, Hill, AR, Ibrahim, MM, Ahmed, M, Cleary, DW, Pandey, AK, Humphries, HE, Allen, L, de Graaf, H, Maiden, M, Faust, SN, Gorringe, AR, Read, RC
Format:	Journal article
Sprache:	English
Veröffentlicht:	American Association for the Advancement of Science 2021

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