A recombinant commensal bacteria elicits heterologous antigen-specific immune responses during pharyngeal carriage
The human nasopharynx contains a stable microbial ecosystem of commensal and potentially pathogenic bacteria, which can elicit protective primary and secondary immune responses. Experimental intranasal infection of human adults with the commensal Neisseria lactamica produced safe, sustained pharynge...
主要な著者: | Laver, JR, Gbesemete, D, Dale, AP, Pounce, ZC, Webb, CN, Roche, EF, Guy, JM, Berreen, G, Belogiannis, K, Hill, AR, Ibrahim, MM, Ahmed, M, Cleary, DW, Pandey, AK, Humphries, HE, Allen, L, de Graaf, H, Maiden, M, Faust, SN, Gorringe, AR, Read, RC |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
American Association for the Advancement of Science
2021
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