A global core outcome measurement set for snakebite clinical trials
Snakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation. A globally representative group of key stakeholders came together to reach consensus on a globally relevant set of core outcome measurements. Outcome domains and outcome measurem...
| Hlavní autoři: | , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Další autoři: | |
| Médium: | Journal article |
| Jazyk: | English |
| Vydáno: |
Elsevier
2023
|
| _version_ | 1826313258101899264 |
|---|---|
| author | Abouyannis, M Esmail, H Hamaluba, M Ngama, M Mwangudzah, H Mumba, N Yeri, BK Mwalukore, S Alphan, HJ Aggarwal, D Alcoba, G Cammack, N Chippaux, J-P Coldiron, ME Gutierrez, JM Habib, AG Harrison, RA Ibister, GK Lavonas, EJ Martins, D Ribeiro, I Watson, JA Williams, DJ Casewell, NR Walker, SA Lalloo, DG |
| author2 | Snakebite Global Core Outcome Set Study Group |
| author_facet | Snakebite Global Core Outcome Set Study Group Abouyannis, M Esmail, H Hamaluba, M Ngama, M Mwangudzah, H Mumba, N Yeri, BK Mwalukore, S Alphan, HJ Aggarwal, D Alcoba, G Cammack, N Chippaux, J-P Coldiron, ME Gutierrez, JM Habib, AG Harrison, RA Ibister, GK Lavonas, EJ Martins, D Ribeiro, I Watson, JA Williams, DJ Casewell, NR Walker, SA Lalloo, DG |
| author_sort | Abouyannis, M |
| collection | OXFORD |
| description | Snakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation. A globally representative group of key stakeholders came together to reach consensus on a globally relevant set of core outcome measurements. Outcome domains and outcome measurement instruments were identified through searching the literature and a systematic review of snakebite clinical trials. Outcome domains were shortlisted by use of a questionnaire and consensus was reached among stakeholders and the patient group through facilitated discussions and voting. Five universal core outcome measures should be included in all future snakebite clinical trials—mortality, WHO disability assessment scale, patient-specific functional scale, acute allergic reaction by Brown criteria, and serum sickness by formal criteria. Additional syndrome-specific core outcome measures should be used depending on the biting species. This core outcome measurement set provides global standardisation, supports the priorities of patients and clinicians, enables meta-analysis, and is appropriate for use in low-income and middle-income settings.
|
| first_indexed | 2024-03-07T07:34:38Z |
| format | Journal article |
| id | oxford-uuid:3dcb021e-ee4a-496f-9e67-0a99d1e5bc07 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-09-25T04:10:15Z |
| publishDate | 2023 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:3dcb021e-ee4a-496f-9e67-0a99d1e5bc072024-06-18T18:07:34ZA global core outcome measurement set for snakebite clinical trialsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:3dcb021e-ee4a-496f-9e67-0a99d1e5bc07EnglishSymplectic ElementsElsevier2023Abouyannis, MEsmail, HHamaluba, MNgama, MMwangudzah, HMumba, NYeri, BKMwalukore, SAlphan, HJAggarwal, DAlcoba, GCammack, NChippaux, J-PColdiron, MEGutierrez, JMHabib, AGHarrison, RAIbister, GKLavonas, EJMartins, DRibeiro, IWatson, JAWilliams, DJCasewell, NRWalker, SALalloo, DGSnakebite Global Core Outcome Set Study GroupSnakebite clinical trials have often used heterogeneous outcome measures and there is an urgent need for standardisation. A globally representative group of key stakeholders came together to reach consensus on a globally relevant set of core outcome measurements. Outcome domains and outcome measurement instruments were identified through searching the literature and a systematic review of snakebite clinical trials. Outcome domains were shortlisted by use of a questionnaire and consensus was reached among stakeholders and the patient group through facilitated discussions and voting. Five universal core outcome measures should be included in all future snakebite clinical trials—mortality, WHO disability assessment scale, patient-specific functional scale, acute allergic reaction by Brown criteria, and serum sickness by formal criteria. Additional syndrome-specific core outcome measures should be used depending on the biting species. This core outcome measurement set provides global standardisation, supports the priorities of patients and clinicians, enables meta-analysis, and is appropriate for use in low-income and middle-income settings. |
| spellingShingle | Abouyannis, M Esmail, H Hamaluba, M Ngama, M Mwangudzah, H Mumba, N Yeri, BK Mwalukore, S Alphan, HJ Aggarwal, D Alcoba, G Cammack, N Chippaux, J-P Coldiron, ME Gutierrez, JM Habib, AG Harrison, RA Ibister, GK Lavonas, EJ Martins, D Ribeiro, I Watson, JA Williams, DJ Casewell, NR Walker, SA Lalloo, DG A global core outcome measurement set for snakebite clinical trials |
| title | A global core outcome measurement set for snakebite clinical trials |
| title_full | A global core outcome measurement set for snakebite clinical trials |
| title_fullStr | A global core outcome measurement set for snakebite clinical trials |
| title_full_unstemmed | A global core outcome measurement set for snakebite clinical trials |
| title_short | A global core outcome measurement set for snakebite clinical trials |
| title_sort | global core outcome measurement set for snakebite clinical trials |
| work_keys_str_mv | AT abouyannism aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT esmailh aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT hamalubam aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT ngamam aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT mwangudzahh aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT mumban aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT yeribk aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT mwalukores aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT alphanhj aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT aggarwald aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT alcobag aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT cammackn aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT chippauxjp aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT coldironme aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT gutierrezjm aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT habibag aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT harrisonra aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT ibistergk aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT lavonasej aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT martinsd aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT ribeiroi aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT watsonja aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT williamsdj aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT casewellnr aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT walkersa aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT lalloodg aglobalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT abouyannism globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT esmailh globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT hamalubam globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT ngamam globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT mwangudzahh globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT mumban globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT yeribk globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT mwalukores globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT alphanhj globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT aggarwald globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT alcobag globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT cammackn globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT chippauxjp globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT coldironme globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT gutierrezjm globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT habibag globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT harrisonra globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT ibistergk globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT lavonasej globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT martinsd globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT ribeiroi globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT watsonja globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT williamsdj globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT casewellnr globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT walkersa globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials AT lalloodg globalcoreoutcomemeasurementsetforsnakebiteclinicaltrials |