Somatic point mutations in RUNX1/CBFA2/AML1 are common in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia

Somatic point mutations in RUNX1/CBFA2/AML1 are common in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia

عرض إصدارات أخرى (1)

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Steensma, D, Gibbons, R, Mesa, R, Tefferi, A, Higgs, D
التنسيق:	Conference item
منشور في:	2004

مواد مشابهة

Somatic point mutations in RUNX1/CBFA2/AML1 are common in high-risk myelodysplastic syndrome, but not in myelofibrosis with myeloid metaplasia.
حسب: Steensma, D, وآخرون
منشور في: (2005)

RUNX1::CBFA2T2 rearranged acute myeloid leukemia transformed from JAK2 V617F mutated primary myelofibrosis
حسب: Lina Han, وآخرون
منشور في: (2024-12-01)

DHPLC analysis of the ATRX gene in myelodysplastic syndrome (MDS) associated with acquired alpha thalassemia (AT-MDS): Novel mutation detection despite somatic mosaicism.
حسب: Steensma, D, وآخرون
منشور في: (2003)

Acquired somatic ATRX mutations in myelodysplastic syndrome associated with alpha thalassemia (ATMDS) convey a more severe hematologic phenotype than germline ATRX mutations.
حسب: Steensma, D, وآخرون
منشور في: (2004)

Acquired alpha-thalassemia in association with myelodysplastic syndrome and other hematologic malignancies.
حسب: Steensma, D, وآخرون
منشور في: (2005)

Prognostic relevance of anemia and transfusion dependency in myelodysplastic syndromes and primary myelofibrosis
حسب: Animesh Pardanani, وآخرون
منشور في: (2011-01-01)

The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells
حسب: Nordheim Alfred, وآخرون
منشور في: (2004-08-01)

Marrow Fibrosis Does Not Account for Circulating CD34+ Cells in Myelofibrosis with Myeloid Metaplasia
حسب: Scott J. Samuelson, وآخرون
منشور في: (2007-04-01)

Hemophagocytic Lymphohistiocytosis in RUNX1: : RUNX1T1 Positive AML with Blast Count Below 20%
حسب: Xingqin Huang, وآخرون
منشور في: (2023-08-01)

Transformation of myelodysplastic syndrome (MDS) to acute myeloid leukaemia (AML)
حسب: Goh, Chermaine Yu Zhen
منشور في: (2021)

Prevalence of erythrocyte hemoglobin H inclusions in unselected patients with myelodysplastic syndromes or myeloproliferative disorders
حسب: Steensma, P, وآخرون
منشور في: (2007)

Screening for myeloid mutations in patients with myelodysplastic syndromes and AML with myelodysplasia-related changes
حسب: Matheus F. Bezerra, وآخرون
منشور في: (2022-07-01)

Molecular characterization of AML with RUNX1-RUNX1T1 at diagnosis and relapse reveals net loss of co-mutations
حسب: Alexander Höllein, وآخرون
منشور في: (2019-02-01)

A novel splicing mutation in the gene encoding the chromatin-associated factor ATRX associated with acquired hemoglobin H disease in myelodysplastic syndrome (ATMDS)
حسب: Steensma, D, وآخرون
منشور في: (2004)

Reduction of RUNX1 transcription factor activity by a CBFA2T3-mimicking peptide: application to B cell precursor acute lymphoblastic leukemia
حسب: Hélène Jakobczyk, وآخرون
منشور في: (2021-03-01)

RUNX1-ETO and RUNX1-EVI1 Differentially Reprogram the Chromatin Landscape in t(8;21) and t(3;21) AML
حسب: Justin Loke, وآخرون
منشور في: (2017-05-01)

Molecular profiling of acute myeloid leukemia with Runx1-Runx1t1 fusion
حسب: Magdy Elbordiny, وآخرون
منشور في: (2024-12-01)

The spectrum of molecular aberrations in myelodysplastic syndromes: in the shadow of acute myeloid leukemia
حسب: David P. Steensma
منشور في: (2007-06-01)

Deletion of the alpha-globin gene cluster as a cause of acquired alpha-thalassemia in myelodysplastic syndrome.
حسب: Steensma, D, وآخرون
منشور في: (2004)

A novel mutation in the last exon of ATRX in a patient with alpha-thalassemia myelodysplastic syndrome.
حسب: Costa, D, وآخرون
منشور في: (2006)

Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1.
حسب: Shinobu Tsuzuki, وآخرون
منشور في: (2007-05-01)

A RUNX1: RUNX1T1 AML with a simultaneous false positive KMT2A rearrangement: FISH interpretation pitfalls
حسب: Chi Zhang, وآخرون
منشور في: (2024-12-01)

An update on the molecular pathogenesis and potential therapeutic targeting of AML with t(8;21)(q22;q22.1);RUNX1-RUNX1T1
حسب: Sayer Al-Harbi, وآخرون
منشور في: (2020-01-01)

Prognosis of RUNX1-RUNX1T1 Rearrangement in Newly Diagnosed Acute Myeloid Leukemia Patients
حسب: Halima Babar, وآخرون
منشور في: (2023-10-01)

Volunteer unrelated donor cell‐derived acute myeloid leukemia with RUNX1‐RUNX1T1
حسب: Shinya Hagiwara, وآخرون
منشور في: (2021-05-01)

The development of pevonedistat in myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML): hope or hype?
حسب: Anson Snow, وآخرون
منشور في: (2022-07-01)

Machine Learning Strategies for Drug Discovery in AML: Focus on RUNX1 Bioactivity
حسب: Deepesh Kumar Verma
منشور في: (2024-03-01)

Germline RUNX1 Intragenic Deletion: Implications for Accurate Diagnosis of FPD/AML
حسب: Nicolas Duployez, وآخرون
منشور في: (2019-06-01)

LLA em portadores de Síndrome de Down e TEL/AML1(ETV6/RUNX1) Acute lymphoblastic leukemia in Down syndrome and TEL/AML1(ETV6/RUNX1)
حسب: Maria de Lourdes L. F. Chauffaille
منشور في: (2009-01-01)

Two novel somatic mutations of the ATRX gene in female patients with acquired alpha thalassemia of myelodysplastic syndrome (ATMDS).
حسب: Haas, P, وآخرون
منشور في: (2006)

Myelodysplastic syndrome due to somatic GATA1 mutation.
حسب: Freson, K, وآخرون
منشور في: (2004)

Hh/Gli antagonist in acute myeloid leukemia with CBFA2T3-GLIS2 fusion gene
حسب: Riccardo Masetti, وآخرون
منشور في: (2017-01-01)

Absence of mutations in the key megakaryocyte transcriptional regulator FOG-1 in patients with idiopathic myelofibrosis.
حسب: Fisher, C, وآخرون
منشور في: (2004)

Primary myelofibrosis and its paraneoplastic stromal effects
حسب: Ayalew Tefferi
منشور في: (2007-05-01)

Mutational cooperativity of RUNX1::RUNX1T1 isoform 9a and oncogenic NRAS in zebrafish myeloid leukaemia
حسب: Robyn Lints, وآخرون
منشور في: (2024-09-01)

Prevalence of erythrocyte haemoglobin H inclusions in unselected patients with clonal myeloid disorders.
حسب: Steensma, D, وآخرون
منشور في: (2007)

Comprehensive Mutation Profile in Acute Myeloid Leukemia Patients with RUNX1-RUNX1T1 or CBFB-MYH11 Fusions
حسب: Wei Qin, وآخرون
منشور في: (2022-05-01)

Acute myeloid leukemia with concurrent NPM1 and RUNX1 mutations
حسب: Zhuang Zuo, وآخرون
منشور في: (2023-01-01)

Dysregulated innate immune signaling cooperates with RUNX1 mutations to transform an MDS-like disease to AML
حسب: Laura Barreyro, وآخرون
منشور في: (2024-06-01)

Cdk6 blocks myeloid differentiation by interfering with Runx1 DNA binding and Runx1-C/EBPalpha interaction.
حسب: Fujimoto, T, وآخرون
منشور في: (2007)