Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity.

CD4+CD25+ regulatory T cells (Treg) are known to influence T cell responses to tumours. Here we have explored the role of Treg in inhibiting not only adaptive, but also innate immune responses to tumours. To this end we used a Fas ligand (FasL)-expressing melanoma cell line in a mouse model. In this...

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書目詳細資料
Main Authors: Simon, A, Jones, E, Richards, H, Wright, K, Betts, G, Godkin, A, Screaton, G, Gallimore, A
格式: Journal article
語言:English
出版: 2007