The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.

BACKGROUND: p53 mutations are frequently observed in colorectal carcinomas but they have also been found in colorectal adenomas, although considerably less frequently. AIMS: To explore p53 mutations in benign tumours, we have screened 70 colorectal adenomas for allelic loss at, and point mutations i...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hao, X, Frayling, I, Sgouros, J, Du, M, Willcocks, T, Talbot, I, Tomlinson, I
التنسيق: Journal article
اللغة:English
منشور في: 2002