The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.

The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.

BACKGROUND: p53 mutations are frequently observed in colorectal carcinomas but they have also been found in colorectal adenomas, although considerably less frequently. AIMS: To explore p53 mutations in benign tumours, we have screened 70 colorectal adenomas for allelic loss at, and point mutations i...

Полное описание

Библиографические подробности
Главные авторы:	Hao, X, Frayling, I, Sgouros, J, Du, M, Willcocks, T, Talbot, I, Tomlinson, I
Формат:	Journal article
Язык:	English
Опубликовано:	2002

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