The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.
BACKGROUND: p53 mutations are frequently observed in colorectal carcinomas but they have also been found in colorectal adenomas, although considerably less frequently. AIMS: To explore p53 mutations in benign tumours, we have screened 70 colorectal adenomas for allelic loss at, and point mutations i...
المؤلفون الرئيسيون: | Hao, X, Frayling, I, Sgouros, J, Du, M, Willcocks, T, Talbot, I, Tomlinson, I |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2002
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مواد مشابهة
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Loss of heterozygosity at APC and beta-catenin expression in sporadic colorectal carcinogenesis
حسب: Hao, X, وآخرون
منشور في: (1998) -
Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.
حسب: Beck, N, وآخرون
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Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma.
حسب: Hao, X, وآخرون
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Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.
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منشور في: (2002) -
APC mutations are sufficient for the growth of early colorectal adenomas.
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