The spectrum of p53 mutations in colorectal adenomas differs from that in colorectal carcinomas.
BACKGROUND: p53 mutations are frequently observed in colorectal carcinomas but they have also been found in colorectal adenomas, although considerably less frequently. AIMS: To explore p53 mutations in benign tumours, we have screened 70 colorectal adenomas for allelic loss at, and point mutations i...
Main Authors: | Hao, X, Frayling, I, Sgouros, J, Du, M, Willcocks, T, Talbot, I, Tomlinson, I |
---|---|
格式: | Journal article |
语言: | English |
出版: |
2002
|
相似书籍
-
Loss of heterozygosity at APC and beta-catenin expression in sporadic colorectal carcinogenesis
由: Hao, X, et al.
出版: (1998) -
Frequency of germline hereditary non-polyposis colorectal cancer gene mutations in patients with multiple or early onset colorectal adenomas.
由: Beck, N, et al.
出版: (1997) -
Reduced expression of molecules of the cadherin/catenin complex in the transition from colorectal adenoma to carcinoma.
由: Hao, X, et al.
出版: (1997) -
Beta-catenin expression and allelic loss at APC in sporadic colorectal carcinogenesis.
由: Hao, X, et al.
出版: (2002) -
APC mutations are sufficient for the growth of early colorectal adenomas.
由: Lamlum, H, et al.
出版: (2000)