Activated regulatory T-cells, dysfunctional and senescent T-cells hinder the immunity in pancreatic cancer

Pancreatic cancer has one of the worst prognoses of any human malignancy and leukocyte infiltration is a major prognostic marker of the disease. As current immunotherapies confer negligible survival benefits, there is a need to better characterise leukocytes in pancreatic cancer to identify better t...

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Bibliographic Details
Main Authors: Sivakumar, S, Abu-Shah, E, Ahern, DJ, Arbe-Barnes, EH, Jainarayanan, AK, Mangal, N, Reddy, S, Rendek, A, Easton, A, Kurz, E, Silva, M, Soonawalla, Z, Heij, LR, Bashford-Rogers, R, Middleton, MR, Dustin, ML
Format: Journal article
Language:English
Published: MDPI 2021

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