No association between polymorphisms in the INSIG1 gene and the risk of type 2 diabetes and related traits.

BACKGROUND: The insulin-induced gene 1 (INSIG1) encodes a protein that blocks proteolytic activation of sterol regulatory element binding proteins, which are transcription factors that activate genes that regulate cholesterol, fatty acid, and glucose metabolism. OBJECTIVE: We tested for associations...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Szopa, M, Meirhaeghe, A, Luan, J, Moreno, L, Gonzalez-Gross, M, Vidal-Puig, A, Cooper, C, Hagen, R, Amouyel, P, Wareham, N, Loos, R
Format: Journal article
Sprog:English
Udgivet: 2010