Investigating the role of serine-ADP-ribosylation in human cells

<p>ADP-ribosylation (ADPr) is a widespread post-translational modification that controls many cellular processes, in particular DNA repair. Poly(ADP-ribose) polymerase 1 (PARP1) is the main ADPr enzyme that performs about 85-90% of DNA damage-induced ADPr. In response to DNA damage, PARP1 rapi...

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Hlavní autor: Prokhorova, E
Další autoři: Ahel, I
Médium: Diplomová práce
Jazyk:English
Vydáno: 2022