Investigating the role of serine-ADP-ribosylation in human cells
<p>ADP-ribosylation (ADPr) is a widespread post-translational modification that controls many cellular processes, in particular DNA repair. Poly(ADP-ribose) polymerase 1 (PARP1) is the main ADPr enzyme that performs about 85-90% of DNA damage-induced ADPr. In response to DNA damage, PARP1 rapi...
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| Format: | Thesis |
| Sprog: | English |
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2022
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