Investigating the role of serine-ADP-ribosylation in human cells

<p>ADP-ribosylation (ADPr) is a widespread post-translational modification that controls many cellular processes, in particular DNA repair. Poly(ADP-ribose) polymerase 1 (PARP1) is the main ADPr enzyme that performs about 85-90% of DNA damage-induced ADPr. In response to DNA damage, PARP1 rapi...

Descripción completa

Detalles Bibliográficos
Autor principal: Prokhorova, E
Otros Autores: Ahel, I
Formato: Tesis
Lenguaje:English
Publicado: 2022