Antidepressant drug treatment induces Arc gene expression in the rat brain.

The mechanism underlying the therapeutic effect of antidepressants is not known but neuroadaptive processes akin to long-term potentiation have been postulated. Arc (Activity-regulated, cytoskeletal-associated protein) is an effector immediate early gene implicated in LTP and other forms of neuropla...

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Autori principali: Pei, Q, Zetterström, T, Sprakes, M, Tordera, R, Sharp, T
Natura: Journal article
Lingua:English
Pubblicazione: 2003

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